The current limited evidence suggests that short-acting statins should be given in the evening whereas long-acting. The dosage of atorvastatin needs. Pin On Lower Cholesterol When Is The Best Time To Take Atorvastatin The LDL goal is to achieve a concentration between 70 and 130 mgdL. . Lovastatin Mevacor fluvastatin the standard-release tablet pravastatin Pravachol simvastatin Zocor. Certain statins work better when taken with a meal. Simvastatin Zocor Lovastatin Mevacor Pravastatin Pravachol Immediate-release fluvastatin Lescol. Short-acting statins include. Take once daily. Others work best when. How and when to take it. Individual patients may need lower levels of atorvastatin based on their risk. Ad Learn About an LDL Medication that Combines with a Statin to Help Reduce Risk. This is because most of the cholesterol our body produces occurs at. Some statins can be taken at any time of...